Your shopping cart is empty!
Anti-CK1 epsilon Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CK1 epsilon rabbit polyclonal antibody |
Gene Name: | Casein kinase I isoform epsilon |
Synonyms: | Csnk1e, Casein kinase 1 epsilon, Casein kinase I, CKI epsilon, CSNK1E, DBT, KC1E |
Immunogen: | Recombinant protein corresponding to Mouse CK1 epsilon |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 47 kDa |
Observed MW. | 47 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, heart, cerebral cortex |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | colon cancer, heart, lung, lung cancer |
Background
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.
Images
|
|
Western blot analysis of CKIe (GB11879) at dilution of 1: 500 |
 | Immunohistochemistry of paraffin embedded human colon cancer using CK1e (GB11879) at dilution of 1: 1500 (200x lens) |
 | Immunohistochemistry of paraffin embedded human lung cancer using CK1e (GB11879) at dilution of 1: 1500 (300x lens) |
|
|
Immunofluorescence of paraffin embedded mouse lung using CK1e (GB11879) at dilution of 1: 1600 (250x lens) |
|
|
Immunofluorescence of paraffin embedded rat heart using CK1e (GB11879) at dilution of 1: 1500 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
