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| Reactivity: | H,M,R & H,M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CLPP rabbit polyclonal antibody |
Gene Name: | ATP-dependent Clp protease proteolytic subunit, mitochondrial |
Synonyms: | Endopeptidase Clp, clpP, ATP dependent proteolytic subunit homolog, Putative ATP-dependent Clp protease proteolytic subunit, ATP dependent proteolytic subunit homolog |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CLPP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Predicted MW. | 30 kDa |
Observed MW. | 25 kDa |
Uniprot ID: | O88696 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 3000 | heart, liver, lung |
IHC/IF | Human, Mouse | 1: 500-1: 3000 | kidney |
Background
Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion.
Images
| Western blot analysis of CLPP (GB113918) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded human kidney using CLPP (GB113918) at dilution of 1: 1500 (400x lens) |
| Immunofluorescence of paraffin embedded embedded human kidney using CLPP (GB113918) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded embedded mouse kidney using CLPP (GB113918) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
