Reactivity: | R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CNPase rabbit polyclonal antibody |
Gene Name: | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
Synonyms: | CNP, CNPase, Cnp1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CNPase |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Predicted MW. | 47 kDa |
Observed MW. | 47 kDa |
Uniprot ID: | P16330 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Rat | 1: 500-1: 1000 | brain, cerebellum, hippocampus |
IHC/IF | Mouse, Rat | 1: 500-1: 1000 | cerebellum, corpus striatum, ganglion, hippocampus, spinal cord |
Background
CNP(2',3'-cyclic-nucleotide 3'-phosphodiesterase) belongs to the cyclic nucleotide phosphodiesterase family. It plays an essential role in axonal survival but not in myelin assembly, coupling oligodendroglial functions in axonal support and myelination. CNP is the third most abundant protein in central nervous system myelin.
Images
Western blot analysis of CNP (GB112623) at dilution of 1: 500 | |
Immunofluorescence of paraffin embedded mouse hippocampus using CNP (GB112623) at dilution of 1: 500 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spinal cord using CNP (GB112623) at dilution of 1: 500 (450x lens) | |
Immunofluorescence of paraffin embedded rat cerebellum using CNP (GB112623) at dilution of 1: 500 (400x lens) | |
Immunofluorescence of paraffin embedded rat corpus striatum using CNP (GB112623) at dilution of 1: 500 (450x lens) | |
Immunofluorescence of paraffin embedded rat ganglion using CNP (GB112623) at dilution of 1: 500 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |