Reactivity: | H,M & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | COMMD4 rabbit polyclonal antibody |
Gene Name: | COMM domain-containing protein 4 |
Synonyms: | Commd4, COMM domain containing 4 |
Immunogen: | Recombinant protein corresponding to Mouse COMMD4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 22 kDa |
Observed MW. | 22 kDa |
Uniprot ID: | Q9CQ02 |
Applications
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 250-1: 500 | kidney, heart, testis |
IHC/IF | Mouse, Rat | 1: 800-1: 3000 | testis |
Background
COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. Down-regulates activation of NF-kappa-B.
Images
Western blot analysis of COMMD4 (GB112284) at dilution of 1: 250 | |
Immunohistochemistry of paraffin embedded mouse testis using COMMD4 (GB112284) at dilution of 1: 800 (300x lens) | |
Immunohistochemistry of paraffin embedded rat testis using COMMD4 (GB112284) at dilution of 1: 800 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |