Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Prostaglandin G/H synthase 2 |
Synonyms: | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin-endoperoxide synthase 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse COX2 |
Uniprot ID: | Q05769 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 69 kDa / 74 kDa |
Product Usage Information
WB | Mouse | 1: 1000-1: 3000 | RAW264.7 |
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Images
WB analysis of COX2/ Cyclooxygenase 2(GB115672). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |