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Anti-CPLX2 Rabbit pAb (100 μl)
| Reactivity: | H,M & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Complexin-2 |
Synonyms: | 921 L, complexin 2, Complexin II, CPLX2, CPX 2, CPX II, CPX2, Hfb1, Synaphin 1 |
Immunogen: | Recombinant protein corresponding to Mouse CPLX2 |
Uniprot ID: | P84086 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. / Observed MW. | 15 kDa / 17 kDa |
Product Usage Information
WB | Human, Mouse | 1: 2000-1: 3000 | cerebellum, spinal cord |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 1400 | gastric neuroendocrine tumor, adrenal gland |
Background
Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis . Although not essential for development, seems critical for the acquisition of higher cognitive functions in the adult brain.
Images
| Western blot analysis of CPLX2 (GB114465) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin embedded human gastric neuroendocrine tumor using CPLX2 (GB114465) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin embedded rat adrenal gland using CPLX2 (GB114465) at dilution of 1: 700 |
| Immunofluorescence analysis of paraffin embedded human gastric neuroendocrine tumor using CPLX2 (GB114465) at dilution of 1: 700 |
| Immunofluorescence analysis of paraffin embedded mouse cerebellum using CPLX2 (GB114465) at dilution of 1: 700 |
| Immunofluorescence analysis of paraffin embedded rat cerebellum using CPLX2 (GB114465) at dilution of 1: 700 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
