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| Reactivity: | H,M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CREB rabbit polyclonal |
Gene Name: | Cyclic AMP-responsive element-binding protein 1 |
Synonyms: | CREB1, CREB, CREB-1, cAMP responsive element binding protein 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CREB1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 200-1: 1000 | lung, liver, kidney |
IF | Human | 1: 200-1: 800 | lung, liver, kidney |
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Images
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using CREB(GB11236) at dilution of 1:400 |
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Immunohistochemistry analysis of paraffin-embedded human liver using CREB(GB11236) at dilution of 1:400 |
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Immunohistochemistry analysis of paraffin-embedded human liver cancer using CREB(GB11236) at dilution of 1:400 |
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Immunohistochemistry analysis of paraffin-embedded human kidney using CREB(GB11236) at dilution of 1:400 |
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Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CREB(GB11236) at dilution of 1:400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
