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Anti-CTBP2 Rabbit pAb (100 μl)
| Reactivity: | H & H,M,R & H,M |
| Applications: | WB & IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | C-terminal-binding protein 2 |
Synonyms: | CTBP2, ribeye |
Immunogen: | KLH conjugated Synthetic peptidecorresponding to Mouse CTBP2 |
Uniprot ID: | P56546 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell junction, Nucleus, Synapse |
Predicted MW. / Observed MW. | 49 kDa / 49 kDa |
Product Usage Information
WB | Human | 1: 300-1: 600 | testis |
IHC/IF | Human, Mouse, Rat | 1: 900-1: 1800 | colon cancer, ovarian cancer, thyroid gland |
ICC/IF | Human, Mouse | 1: 100-1: 400 | NIH-3T3 |
Background
C-Terminal binding protein 2 (CTBP2) is a transcriptional repressor. It contains a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. This protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggested that this protein is involved in transcriptional repression. CTBP2 is expressed in all tissues tested, with a higher level of expression in the heart, skeletal muscle, and pancreas. The gene of CTBP2 is mapped to human chromosome 21q21.3.
Images
| Western blot analysis of CTBP2 (GB113724) at dilution of 1: 600 |
| Western blot analysis of CTBP2 (GB113724) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded human colon cancer using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded human thyroid gland using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded mouse duodenum using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded rat duodenum using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded mouse testis using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded rat testis using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded human tumor using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded human tumor using CTBP2 (GB113724) at dilution of 1: 1800 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using CTBP2 (GB113724) at dilution of 1:100-1:400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
