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Anti-Calponin 2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Calponin 2 rabbit polyclonal antibody |
Gene Name: | Calponin-2 |
Synonyms: | Neutral calponin, Cnn2, smooth muscle, Calponin H2 |
Immunogen: | Recombinant protein corresponding to Mouse Calponin 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 33 kDa |
Observed MW. | 33 kDa |
Uniprot ID: | Q08093 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | stomach, lung, lymph node |
Background
Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II.
Images
| Western blot analysis of CNN2 (GB112100) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
