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Anti-Cathepsin V Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cathepsin V rabbit polyclonal |
Gene Name: | Cathepsin L2 |
Synonyms: | Cathepsin U, Cathepsin V, CTSV, CATL2, CTSL2, CTSU |
Immunogen: | Recombinant protein corresponding to Human Cathepsin V |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Lysosome |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 1000-1: 2000 | kidney, duodenum |
IF | Human, Mouse, Rat | 1: 300-1: 600 | kidney |
Background
Cathepsin V is a lysosomal cysteine protease which has an important role in corneal physiology.Cathepsin V was found to be differentially expressed in relation to pigmentary skin backgrounds, and was about 7.5-folds higher in keratinocytes from lightly pigmented, relative to darkly pigmented skins. It is expressed in primary keratinocytes, melanocytes, and HaCaT keratinocytes, but not in primary fibroblasts. The purified cathepsin L2 was a high molecular weight proteinase of about 78 kDa, but it was unstable to SDS and reducing conditions, which dissociated parts of the proteinase into 66 kDa, 31 kDa and 26 kDa fragments(Food Chemistry,Volume11,Issue4,879-886) and it can form a complex of 70 kDa with an unidentified subunit.
Images
| Immunohistochemistry analysis of paraffin-embedded human kidney using CTSV (GB112712) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using CTSV (GB112712) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using CTSV (GB112712) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded rat duodenum using CTSV (GB112712) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using CTSV (GB112712) at dilution of 1: 600 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using CTSV (GB112712) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
