Your shopping cart is empty!
Anti-Chemerin Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Chemerin rabbit polyclonal antibody |
Gene Name: | Retinoic acid receptor responder protein 2 |
Synonyms: | Chemerin, Rarres2, HP10433, RAR responsive protein TIG2, TIG2 |
Immunogen: | Recombinant protein corresponding to Mouse Chemerin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 18 kDa |
Observed MW. | 15 kDa |
Uniprot ID: | Q9DD06 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | kidney, brown adipose |
Background
Chemerin, also named as TIG2 and RARRES2, is adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1). Its other ligands include G protein-coupled receptor 1 (GPR1) and chemokine receptor-like 2 (CCRL2). It positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. RARRES2 have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. The MW of Chemerin is 14-19 kDa.
Images
| Western blot analysis of RARRES2 (GB111909) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
