Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Choline Acetyltransferase rabbit polyclonal antibody |
Gene Name: | Choline O-acetyltransferase |
Synonyms: | CHOACTase, CHAT, Choline acetylase, Acetyl CoA:choline O acetyltransferase, CMS1A |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Choline Acetyltransferase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 72 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | P28329, Q03059, P32738 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, cerebellum, hippocampus, cortex |
Background
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea.
Images
Western blot analysis of CHAT (GB112055) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |