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Anti-Cleaved PARP1 Rabbit pAb (100 μl)
| Reactivity: | H & H |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cleaved PARP1 rabbit polyclonal |
Gene Name: | Poly [ADP-ribose] polymerase 1 |
Synonyms: | PARP 1, PARP-1, PARP1, ADPRT, ADPRT1, msPARP, PPOL, ARTD1, PARP, PARP-1, pADPRT-1, oly (ADP ribose) polymerase 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human PARP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 113 kDa |
Observed MW. | 89 kDa |
Uniprot ID: | P09874 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | Hela, staurosporine-treated Hela |
IHC | Human | 1: 400-1: 800 | tonsil, appendix, lymph node, stomach cancer |
Background
PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
Images
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Western blot analysis of PARP1 (GB111503) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded human tonsil using PARP1 (GB111503) at dilution of 1: 750 |
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Immunohistochemistry analysis of paraffin-embedded human appendix using PARP1 (GB111503) at dilution of 1: 750 |
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Immunohistochemistry analysis of paraffin-embedded human lymph node using PARP1 (GB111503) at dilution of 1: 750 |
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Immunohistochemistry analysis of paraffin-embedded human stomach cancer using PARP1 (GB111503) at dilution of 1: 750 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
