Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Colec12 rabbit polyclonal antibody |
Gene Name: | Collectin-12 |
Synonyms: | Collectin placenta protein 1, CL-P1, Scavenger receptor with C-type lectin, Colec12, Clp1, SRCL, SCARA4, hCL-P1 |
Immunogen: | Recombinant protein corresponding to Mouse Colec12 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Uniprot ID: | Q8K4Q8, Q4V885 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | lung, testis |
Background
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
Images
Immunohistochemistry of paraffin embedded mouse lung using COLEC12 (GB112085) at dilution of 1:700 (300x lens) | |
Immunohistochemistry of paraffin embedded rat lung using COLEC12 (GB112085) at dilution of 1:700 (300x lens) | |
Immunofluorescence of paraffin embedded mouse lung using colEC12 (GB112085) at dilution of 1:650 (400x lens) | |
Immunofluorescence of paraffin embedded rat lung using colEC12 (GB112085) at dilution of 1:650 (250x lens) | |
Immunofluorescence of paraffin embedded rat testis using colEC12 (GB112085) at dilution of 1:650 (250x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |