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Anti-Connexin 43 / GJA1 Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Gap junction alpha-1 protein |
Synonyms: | GJA1, AVSD3, CMDR, CX43, EKVP, GJAL, HLHS1, HSS, ODDD, PPKCA, gap junction protein alpha 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Connexin 43 |
Uniprot ID: | P23242 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cell junction, Endoplasmic reticulum |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 300-1: 1200 | heart |
Background
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract .
Images
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Immunofluorescence analysis of paraffin embedded rat heart using Connexin 43 (GB12234) at dilution of 1: 600 |
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Immunofluorescence analysis of paraffin embedded mouse heart using Connexin 43 (GB12234) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
