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Anti-Corticotropin Releasing Factor Receptor 2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Corticotropin Releasing Factor Receptor 2 rabbit polyclonal antibody |
Gene Name: | Corticotropin-releasing factor receptor 2 |
Synonyms: | Crhr2, CRHR2, CRF-RB, CRF2, CRFR2, HM-CRF, corticotropin releasing hormone receptor 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Corticotropin Releasing Factor Receptor 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 48 kDa |
Observed MW. | 48 kDa |
Uniprot ID: | Q60748, P47866 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | heart, muscle |
Background
The protein encoded by the CRHR2 gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Images
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Western blot analysis of CRHR1 (GB11709) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
