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Anti-Cripto1/CRIPTO Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Teratocarcinoma-derived growth factor |
Synonyms: | CRGF, Cripto 1, TDGF1, Cripto-1 growth factor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cripto1/CRIPTO |
Uniprot ID: | P51865 |
Isotype: | lgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 19 kDa / 21 kDa |
Product Usage Information
WB | Human | 1: 300-1: 400 | 293, HeLa, Hep G2 |
Background
GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated Tdgf1 acts as a Nodal coreceptor in cis. Shedding of Tdgf1 by Tmem8a modulates Nodal signaling by allowing soluble Tdgf1 to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.
Images
| WB analysis of Cripto-1 (GB115532). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
