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Anti-Crk p38 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Crk p38 rabbit polyclonal antibody |
Gene Name: | Adapter molecule crk |
Synonyms: | CRK, Crk p38, CRK isoform 2, CrkII; CRKII; p38, Proto oncogene C crk, v crk sarcoma virus CT10 oncogene homolog, Adapter molecule crk, Avian sarcoma virus CT10 |
Immunogen: | Recombinant protein corresponding to Human Adapter molecule crk |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 34 kDa |
Observed MW. | 38 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | HepG2, A549, MCF7, 293T, U87 |
Background
Adapter molecule crk also known as proto-oncogene c-Crk or p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.
Images
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Western blot analysis of crk (GB11645) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
