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Anti-Cytokeratin 14 Mouse mAb (100 μl)
| Reactivity: | H,M & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Keratin, type I cytoskeletal 14 |
Synonyms: | Krt14, KRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 14 |
Uniprot ID: | Q61781 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 53 kDa / 53 kDa |
Product Usage Information
WB | Human, Mouse | 1: 500-1: 1000 | skin |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | skin, bile duct cancer |
Background
Keratin 14, also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14), is a member of the type I keratin family of intermediate filament proteins. The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Images
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Western blot analysis of CK14 (GB12803) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded Human bile duct cancer using CK14 (GB12803) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded Mouse skin using CK14 (GB12803) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded Rat skin using CK14 (GB12803) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
