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Anti-Cytokeratin 6 Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Keratin, type II cytoskeletal 6A |
Synonyms: | CK-6A, CK 6D, CK6A, CK6C, CK6D, Cytokeratin 6A, Cytokeratin 6D, Hom s 5, K6A, K6C, K6D, keratin 6A, KRT conserve, KRT6, KRT6A, KRT6C, KRT6D, Type II keratin Kb6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CK6 |
Uniprot ID: | P02538 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | skin, esophagus, cervical carcinoma, epithelial of oral cavity |
Background
Keratin 6A is a member of the keratin gene family which is one of the 27 different type II keratinsis. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia.
Images
| Immunohistochemistry analysis of paraffin embedded rat skin using CK6 (GB12824) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human esophagus using CK6 (GB12824) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse skin using CK6 (GB12824) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human cervical carcinoma using CK6 (GB12824) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded mouse epithelial of oral cavity using CK6 (GB12824) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
