Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Monoclonal |
Gene Name: | Keratin, type II cytoskeletal 6A |
Synonyms: | CK-6A, CK 6D, CK6A, CK6C, CK6D, Cytokeratin 6A, Cytokeratin 6D, Hom s 5, K6A, K6C, K6D, keratin 6A, KRT conserve, KRT6, KRT6A, KRT6C, KRT6D, Type II keratin Kb6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CK6 |
Uniprot ID: | P02538 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | Skin, esophageal carcinoma |
Background
Keratin 6A is a member of the keratin gene family which is one of the 27 different type II keratinsis. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia.
Images
IHC analysis of Cytokeratin 6(GB151247). | |
IHC analysis of Cytokeratin 6(GB151247). | |
IHC analysis of Cytokeratin 6(GB151247). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |