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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DDX1 rabbit polyclonal antibody |
Gene Name: | ATP-dependent RNA helicase DDX1 |
Synonyms: | DBP-RB, DDX1, DEAD box protein 1, UKVH5d |
Immunogen: | Recombinant protein corresponding to Mouse DDX1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 83 kDa |
Observed MW. | 83 kDa |
Uniprot ID: | Q91VR5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 1000-1: 3000 | testis |
Background
Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation.
Images
 | Western blot analysis of DDX1 (GB113944) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
