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Anti-DEFA6 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Alpha-defensin 6/12 |
Synonyms: | DEF6, DEFA6, Defensin 6, Defensin, alpha 6, defensin, alpha 6, Paneth cell, HD 6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DEFA6 |
Uniprot ID: | P50704 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 4000-1: 8000 | small intestine |
Background
Has broad-spectrum antimicrobial properties. Has antibacterial activity against the Gram-positive bacterium L.monocytogenes EGD and the Gram-negative bacteria E.coli ML-35p and avirulent S.typhimurium 7953, but not against the mouse-virulent S.typhimurium 14028S. Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
Images
| Immunofluorescence of paraffin embedded rat small intestine using Defa6 (GB114861) at dilution of 1: 4000 |
| Immunofluorescence of paraffin embedded mouse small intestine using Defa6 (GB114861) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
