Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DEPDC1 rabbit polyclonal antibody |
Gene Name: | DEP domain-containing protein 1A |
Synonyms: | DEPDC1, DEPDC1A, DEP domain containing 1, SDP35, Cell cycle control protein SDP35 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human DEPDC1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8CIG0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | heart, placenta |
Background
DEPDC1 is a 784 amino acid nuclear protein expressed in testis and up-regulated in bladder cancer cells. Containing a DEP domain and a Rho-GAP domain, DEPDC1 may play an essential role in the growth of bladder cancer cells, and is considered a novel protein target for bladder cancer therapy. Existing as five isoforms produced by alternative splicing events, DEPDC1 is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Images
Immunohistochemistry of paraffin embedded mouse heart using DEPDC1 (GB112008) at dilution of 1:500 (300x lens) | |
Immunohistochemistry of paraffin embedded rat heart using DEPDC1 (GB112008) at dilution of 1:500 (250x lens) | |
Immunofluorescence of paraffin embedded mouse placenta using DEPDC1 (GB112008) at dilution of 1:500 (400x lens) | |
Immunofluorescence of paraffin embedded rat heart using DEPDC1 (GB112008) at dilution of 1:500 (250x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |