Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Dehydrogenase/reductase SDR family member 11 |
Synonyms: | ARPG836, SDR24C1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DHRS11 |
Uniprot ID: | Q3U0B3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 28 kDa / 26 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 3000 | heart, liver, colon |
Background
Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.
Images
Western blot analysis of PHRS11 (GB115128) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |