Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DHX30 rabbit polyclonal antibody |
Gene Name: | ATP-dependent RNA helicase DHX30 |
Synonyms: | DEAH box protein 30, Dhx30, Helg, Putative ATP-dependent RNA helicase DHX30, DDX30, Ret CoR |
Immunogen: | Recombinant protein corresponding to Mouse DHX30 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 137 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q7L2E3 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 250-1: 500 | HeLa, 293T, Jurkat |
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein.
Images
Western blot analysis of DHX30 (GB112024) at dilution of 1: 250 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |