Reactivity: | M,R & M,R |
Applications: | IHC/IF & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DLL3 rabbit polyclonal antibody |
Gene Name: | Delta-like protein 3 |
Synonyms: | pu, pudgy, delta like |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DLL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 65 kDa |
Observed MW. | 65 kDa |
Uniprot ID: | O88516, O88671 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | lung |
Background
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm .
Images
Western blot analysis of DLL3 (GB11321-1) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |