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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Docking protein 5 |
Synonyms: | C20orf180, docking protein 5, DOK5, IRS 6, IRS6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DOK5 |
Uniprot ID: | Q91ZM9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 35 kDa / 35 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 700-1: 2000 | kidney, liver, brain |
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Images
| Western blot analysis of DOK5 (GB114635) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
