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Anti-DUSP9 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DUSP9 rabbit polyclonal |
Gene Name: | Dual specificity protein phosphatase |
Synonyms: | dual specificity phosphatase 9, DUSP9, MAP kinase phosphatase 4, MKP4, Mitogen-activated protein kinase phosphatase 4, serine/threonine specific protein phosphatase |
Immunogen: | Recombinant protein corresponding to Mouse DUSP9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 49 kDa |
Observed MW. | 49 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | liver, kidney |
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.
Images
 | Western blot analysis of DUSP9 (GB113257) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
