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Anti-Dectin-1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | C-type lectin domain family 7 member A |
Synonyms: | Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CD369, Clec7a, Bgr, Clecsf12, Dectin1 |
Immunogen: | Recombinant protein corresponding to Mouse Dectin-1 |
Uniprot ID: | Q6QLQ4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 27 kDa / 38 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, thymus, liver |
Background
CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response.
Images
| Western blot analysis of Dectin-1 (GB111816) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
