Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Density-regulated protein |
Synonyms: | DENR, density regulated protein, DRP, DRP1, Protein DRP1, SMAP 3 |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human DENR |
Uniprot ID: | O43583 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 22 kDa / 27-30 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 500 | heart, lung, skeletal muscle |
Background
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Images
Western blot analysis of DENR (GB115459) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |