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Anti-Dynamin 1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Dynamin 1 rabbit polyclonal antibody |
Gene Name: | Dynamin-1 |
Synonyms: | Dnm1, Dnm, Kiaa4093, B dynamin, D100, Dynamin |
Immunogen: | Recombinant protein corresponding to Mouse Dynamin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 98 kDa |
Observed MW. | 98 kDa |
Uniprot ID: | P39053, P21575 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, hippocampus |
Background
Dynamin is a GTPase required for endocytosis of clathrin coated vesicles from the membrane. Dynamin's involvement in endocytosis was first discovered during the characterization of the temperature sensitive parylytic shibire mutation from Drosophila melanogaster. Three closely related isoforms have been identified in mammals. Dynamin1 is expressed exclusively in neurons, dynamin2 is ubiquitously expressed and dynamin3 is expressed primarily in the testes. Each of these isoforms of dynamin also has several splice variants.
Images
| Western blot analysis of DNM1 (GB111901) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
