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Anti-EFTUD2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EFTUD2 rabbit polyclonal antibody |
Gene Name: | 116 kDa U5 small nuclear ribonucleoprotein component |
Synonyms: | Snrp116, Elongation factor Tu GTP-binding domain-containing protein 2, U5-116 kDa, U5 snRNP-specific protein,116 kDa, EFTUD2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse EFTUD2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 109 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q15029, O08810 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, liver |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | brain, colon cancer, liver, lung, lung cancer, ovarian cancer, ovary, testis |
Background
EFTUD2 encodes the 116 kDa U5 small nuclear ribonecleoprotein (snRNP) component, also named SNU114, it has GTP binding activity and is required for pre-mRNA splicing. Evolutionarily conserved human snRNP protein (U5-116kDa) is homologous to the ribosomal elongation factor EF-2 (ribosomal translocase). Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM).
Images
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Western blot analysis of EFTUD2 (GB111188) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded human colon cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded human lung cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat ovary using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded human ovarian cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse liver using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
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Immunofluorescence of paraffin embedded rat testis using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
