Reactivity: | H |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Epidermal growth factor receptor |
Synonyms: | EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human EGFR |
Uniprot ID: | P00533 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 134 kDa / 175 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 2000 | HepG2 |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Images
![]() | Western blot analysis of EGFR (GB121505) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |