Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | EHMT1/GLP rabbit polyclonal antibody |
Gene Name: | Histone-lysine N-methyltransferase EHMT1 |
Synonyms: | Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, Ehmt1, Euhmtase1, Glp, Kmt1d, G9a-like protein 1, GLP, GLP1, Lysine N-methyltransferase 1D |
Immunogen: | Recombinant protein corresponding to Mouse EHMT1/GLP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 142 kDa |
Observed MW. | 180 kDa |
Uniprot ID: | Q9H9B1, Q5DW34 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | HeLa, MCF-7, HepG2, 293T, HaCaT, NIH/3T3, PC-12 |
Background
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome).
Images
Western blot analysis of EHMT1 (GB112232) at dilution of 1: 500 | |
Western blot analysis of EHMT1 (GB112232) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |