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Anti-EIF3D Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EIF3D rabbit polyclonal antibody |
Gene Name: | Eukaryotic translation initiation factor 3 subunit D |
Synonyms: | eIF3d, Eukaryotic translation initiation factor 3 subunit 7, eIF-3-zeta, eIF3 p66, Eif3d, Eif3s7, subunit 7 zeta, translation initiation factor eIF3 p66, AA407891, eIF3-p66 |
Immunogen: | Recombinant protein corresponding to Mouse EIF3D |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 64 kDa |
Observed MW. | 64 kDa |
Uniprot ID: | O15371, O70194, Q6AYK8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, testis |
Background
eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
Images
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Western blot analysis of EIF3D (GB111544) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |