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Anti-ELAVL3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ELAVL3 rabbit polyclonal antibody |
Gene Name: | ELAV-like protein 3 |
Synonyms: | Hu-antigen C, HuC, Elavl3, HUCL |
Immunogen: | Recombinant protein corresponding to Mouse ELAVL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q60900 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 600-1: 3600 | brain, embryonic mouse |
Background
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Images
| Immunohistochemistry of paraffin embedded mouse brain using ELAVL3 (GB112599) at dilution of 1:1800 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat brain using ELAVL3 (GB112599) at dilution of 1:1800 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using ELAVL3 (GB112599) at dilution of 1:700 (400x lens) |
| Immunofluorescence of paraffin embedded mouse embryonic mouse using ELAVL3 (GB112599) at dilution of 1:700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
