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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG2a, κ |
Clonality: | Monoclonal |
Conjugation: | ER780 |
Synonyms: | Monocyte differentiation antigen CD14,CD14,Myeloid cell-specific leucine-rich glycoprotein |
Background: | CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils. |
Gene ID: | 929 |
SwissProt: | P08571 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
Documents: | Please contact us to request the manual |