Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ERK1 rabbit polyclonal antibody |
Gene Name: | Mitogen-activated protein kinase 3 |
Synonyms: | MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, MNK1, p44-ERK1, Erk1, Prkm3, Mapk3 |
Immunogen: | Recombinant protein corresponding to Mouse ERK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 43 kDa |
Observed MW. | 43 kDa |
Uniprot ID: | Q63844, P21708 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | colon, testis |
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Images
Western blot analysis of MAPK3 (GB112238) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |