Anti-Erlin-2 Rabbit pAb (100 μl)

Anti-Erlin-2 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB114666-100
Availability: In Stock
$259.00
-+
Reactivity: H,M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Gene Name:

Erlin-2

Synonyms:

C8orf2, ER lipid raft associated 2, Erlin 2, ERLIN2, NET32, SPFH2

Immunogen:

KLH conjugated Synthetic peptide corresponding to Mouse Erlin-2

Uniprot ID:

Q8BFZ9

Isotype:

IgG

Purity:

Affinity purification

Predicted MW. / Observed MW.

38 kDa / 43 kDa




Product Usage Information

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, kidney




Background

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex .




Images


Western blot analysis of ERLIN2 (GB114666) at dilution of 1: 1000




Storage

Storage            Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer            PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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