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Anti-Estrogen Related Receptor beta Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Estrogen Related Receptor beta rabbit polyclonal antibody |
Gene Name: | Steroid hormone receptor ERR2 |
Synonyms: | Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2, Esrrb, Err-2, Err2, Nr3b2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Estrogen Related Receptor beta |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 48 kDa |
Observed MW. | 48 kDa |
Uniprot ID: | O95718, Q61539, P11475 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, liver, testis, kidney |
Background
Estrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation.
Images
| Western blot analysis of ESRRB (GB112014) at dilution of 1: 500 |
| Western blot analysis of ESRRB (GB112014) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
