Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Ezrin rabbit polyclonal antibody |
Gene Name: | Ezrin |
Synonyms: | Cytovillin, Villin-2, p81, EZR, VIL2, CVIL, CVL, cytovillin 2, Ezrin |
Immunogen: | Recombinant protein corresponding to Human Ezrin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | P15311 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | brain, colon, epityphlon, kidney, ovarian cancer, stomach |
Background
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers.
Images
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Immunohistochemistry of paraffin embedded human colon using EZrin (GB111200) at dilution of 1:3000 (400x lens) |
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Immunohistochemistry of paraffin embedded human colon using EZrin (GB111200) at dilution of 1:6000 (400x lens) |
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Immunohistochemistry of paraffin embedded human epityphlon using EZrin (GB111200) at dilution of 1:3000 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
![]() | Immunofluorescence of paraffin embedded human ovarian cancer using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
![]() | Immunofluorescence of paraffin embedded mouse kidney using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
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Immunofluorescence of paraffin embedded rat stomach using EZrin (GB111200) at dilution of 1:1100 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |