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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FIF rabbit polyclonal antibody |
Gene Name: | Apoptosis inhibitor 5 |
Synonyms: | API-5, AAC-11, Api5, Migration inducing protein MIG8, MIG 8, API5L1, Antiapoptosis clone 11 protein, FIF |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FIF |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | O35841 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 300-1: 2400 | brain, colon, duodenum, liver cancer, testis |
Background
Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. API5 expression is often upregulated in tumor cells, particularly in metastatic cells. It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription. Alternate Names: AAC 11; AAC11; Antiapoptosis clone 11 protein; API 5; API5; API5 like 1; API5L1; Cell migration inducing gene 8 protein; Fibroblast growth factor 2 interacting factor 2; FIF; MIG 8; MIG8; Migration inducing protein MIG8; Protein XAGL.
Images
 | Immunohistochemistry of paraffin embedded human colon using Api5 (GB112298) at dilution of 1:350 (400x lens) |
| Immunohistochemistry of paraffin embedded human liver cancer using Api5 (GB112298) at dilution of 1:350 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse duodenum using Api5 (GB112298) at dilution of 1:350 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse testis using Api5 (GB112298) at dilution of 1:350 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse brain using Api5 (GB112298) at dilution of 1:400 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse testis using Api5 (GB112298) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded rat testis using Api5 (GB112298) at dilution of 1:400 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
