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Reactivity: | Rat |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | FITC |
Synonyms: | Receptor-type tyrosine-protein phosphatase C,Leukocyte common antigen, LCA, T200, Ly-5,Ptprc |
Background: | CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. |
Gene ID: | 19265 |
SwissProt: | P04157 |
Concentration: | 0.5 mg/mL |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
Documents: | Please contact us to request the manual |