Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | FKLF / KLF11 rabbit polyclonal antibody |
Gene Name: | Krueppel-like factor 11 |
Synonyms: | TGFB-inducible early growth response protein 2b, Transforming growth factor-beta-inducible early growth response protein 3, TGFB-inducible early growth response protein 3, TIEG-3, Klf11, Tieg2b, FKLF |
Immunogen: | Recombinant protein corresponding to Mouse KLF11 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 54 kDa |
Observed MW. | 54 kDa |
Uniprot ID: | Q8K1S5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, kidney, colon |
Background
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
Images
Western blot analysis of KLF11 (GB112221) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |