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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FLCN rabbit polyclonal antibody |
Gene Name: | Folliculin |
Synonyms: | Flcn, FLCN, BHD, FLCL, Folliculin |
Immunogen: | Recombinant protein corresponding to Mouse FLCN |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q8QZS3, Q76JQ2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 250-1: 2000 | heart, kidney, lung, skin, testis |
Background
May play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). May be a tumor suppressor. May be involved in colorectal tumorigenesis. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
Images
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Immunohistochemistry of paraffin embedded mouse heart using FLCN (GB11924) at dilution of 1:1200 (250x lens) |
 | Immunohistochemistry of paraffin embedded mouse lung using FLCN (GB11924) at dilution of 1:1200 (300x lens) |
 | Immunohistochemistry of paraffin embedded rat testis using FLCN (GB11924) at dilution of 1:1200 (250x lens) |
 | Immunofluorescence of paraffin embedded mouse kidney using FLCN (GB11924) at dilution of 1:500 (250x lens) |
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Immunofluorescence of paraffin embedded mouse lung using FLCN (GB11924) at dilution of 1:500 (250x lens) |
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Immunofluorescence of paraffin embedded rat skin using FLCN (GB11924) at dilution of 1:500 (200x lens) |
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Immunofluorescence of paraffin embedded rat testis using FLCN (GB11924) at dilution of 1:500 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
