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| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FMRP rabbit polyclonal |
Gene Name: | Synaptic functional regulator FMR1 |
Synonyms: | Fragile X mental retardation protein 1 homolog, FMRP, Protein FMR-1, mFmr1p, Fmr1, Fmr-1, FRAXA, POF, POF1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FMRP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 600-1: 1200 | prefrontal lobe, cerebellum |
Background
The selective RNA-binding protein FMRP forms a messenger ribonucleoprotein complex that associates with polyribosomes, implicating in regulation of translation. FMR1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to and reperss the mRNA. It also has a role in the transport of mRNA from the nucleus to the cytoplasm. FMR1 exists several isforms and the molecular weight of FMR1 is about 59-72 kDa.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse prefrontal lobe using FMRP (GB113089) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat cerebellum using FMRP (GB113089) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
