Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | FOXO1 rabbit polyclonal |
Gene Name: | Forkhead box protein O1 |
Synonyms: | |
Immunogen: | Recombinant protein corresponding to Mouse FOXO1 |
Isotype: | IgG |
Subcellular location: | |
Purity: | Affinity purification |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 800-1: 1600 | lung cancer, kidney cancer, brain |
IF | Human, Mouse, Rat | 1: 800-1: 1600 | lung cancer, kidney cancer, brain |
Background
FOXO1 is a transcription factor that plays important roles in regulation ofgluconeogenesis and glycogenolysis by insulin signaling, and is also central to the decision for a preadipocyte to commit to adipogenesis. It is primarily regulated through phosphorylation on multiple residues; its transcriptional activity is dependent on its phosphorylation state.
Images
Immunohistochemistry analysis of paraffin-embedded human lung cancer using FOXO1 (GB11286-1) at dilution of 1:800 |
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Immunohistochemistry analysis of paraffin-embedded human colon cancer using FOXO1 (GB11286-1) at dilution of 1:800 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using FOXO1 (GB11286-1) at dilution of 1:800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |