Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Phospholemman |
Synonyms: | FXYD1, Phospholemman, PLM |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FXYD1/PLM |
Uniprot ID: | Q9Z239 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 10 kDa / 15 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 4000 | brain, heart, skeletal muscle, spleen |
Background
Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell . Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated (By similarity). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 . Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone.
Images
Western blot analysis of FXYD1/PLM (GB114316) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |