Reactivity: | M |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Factor XIIIa rabbit polyclonal |
Gene Name: | Coagulation factor XIII A chain |
Synonyms: | Coagulation factor XIIIa, Protein-glutamine gamma-glutamyltransferase A chain, F13A, F13A1, Factor XIIIA, Transglutaminase A chain |
Immunogen: | Recombinant protein corresponding to Mouse Factor XIIIa |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
IHC/IF | Mouse | 1: 1200-1: 2400 | lung, spleen |
Background
Factor XIIIa is a blood proenzyme that catalyzes intermolecular cross-linking of fibrinogen and is involved in clotting cascade. It has been identified in various tissues including placenta, uterus, and prostate. Anti-Factor XIIIa has been found to be useful in differentiating between dermatofibroma (90% positive) and desmoplastic malignant melanoma (negative). Factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor , and meningioma.
Images
Immunohistochemistry analysis of paraffin-embedded mouse lung using Factor XIIIa (GB113293) at dilution of 1: 2400 | |
Immunohistochemistry analysis of paraffin-embedded mouse spleen using Factor XIIIa (GB113293) at dilution of 1: 2400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |